Modafinil (Provigil)![]() |
Phosphatidylserine![]() | |
Modafinil, commonly sold as Provigil, is considered one of the first groundbreaking eugeroic drugs to hit the market. It has been approved by the FDA for the treatment of various wakefulness disorders such as narcolepsy- a condition resulting in excessive daytime sleepiness, obstructive sleep apnea and shift work disorder. For those people without wakefulness disorders, this drug is often used on an off-label basis for cognitive enhancement by means of altering the CNS levels of histamine. Also, research has shown that it boosts working memory, but the long-term effects are relatively unknown. | Phosphatidylserine is considered a phospholipid membrane that is found in every cell of the body and it promotes healthy cellular signaling. This has been used in the treatment for ADD, ADHD and other bipolar disorers while there is some evidence suggesting that it may lower risk of developing dementia or cognitive impairment among the elderly. Also, some believe that it may contain neuroprotective properties, while others suggest better studies need to be conducted before any claims can be verified or disproven. It is thought that phosphatidylserine could raise levels of cognitive enhancing neurotransmitters like acetylcholine and dopamine thus, improving memory and attention. | |
Tradenamesacetamide, Provigil, Modalert, Modapro, Alertex, 2-[Diphenylmethylsulfinyl]acetamide | PS, D-Serine | |
DoseThe standard dosage consists of 200g/day No dosage data available | 300mg (For the treatment of Alzheimer's disease and other age-related memory impairment, a dose of 100mg of phosphatidlyserine taken 3 times daily is recommended.) No dosage data available | |
Side EffectsPotential side effects include headache, insomnia, lack of appetite, hypertension, nervousness, dry mouth, nausea and vomiting. | Phosphatidylserine is generally safe to use and well-tolerated however, potential side effects include insomnia and stomach upset. | |
Classification | Total UsersThere are no users taking this supplement. There are no users taking this supplement. Rated5.00/5 based on 2 user votes 4.00/5 based on 2 user votes Evidence-Based Effects
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